Cyclodextrin-complexed curcumin exhibits anti-inflammatory and antiproliferative activities superior to those of curcumin through higher cellular uptake

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Publication

Retraction

Retraction Case 1

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Resource ID

75

Authors

Vivek R Yadav, Sahdeo Prasad, Ramaswamy Kannappan, Jayaraj Ravindran, Madan M Chaturvedi, Lauri Vaahtera, Jaakko Parkkinen, Bharat B Aggarwal

Publisher

Elsevier

Journal

Biochemical Pharmacology

Subjects

BLS - Basic Life Sciences, HSC - Human Science/Medicine, Biochemistry, Biology - Cellular, Biology - Molecular, Medicine - Pharmacology

Publication Date

23 June 2010

DOI

10.1016/j.bcp.2010.06.022

Manipulation status

Retraction

Retraction DOI

10.1016/j.bcp.2015.11.007

Manipulated Image

1A

Manipiulation category 1

copy-paste

Comment 1

"Figure 1A (3rd lane; CDC) was manipulated by replicating an image of a control lane from Figure 1C (left lane) to represent different experimental conditions" (see Retraction Notice)

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1D

Manipiulation category 2

duplicate - self

Comment 2

"Figure 1D, nuclei isolated from cells in medium (“Nuclei / Medium”), was reused in Figure 1G in reference [1], to represent different experimental conditions (nuclei of cells treated with γ-T3; “Nuclei / γ-T3”)" (see Retraction Notice)
Reference [1]: Kannappan R, Yadav VR, Aggarwal BB γ-Tocotrienol but not γ-tocopherol blocks STAT3 cell signaling pathway through induction of protein-tyrosine phosphatase SHP-1 and sensitizes tumor cells to chemotherapeutic agents J Biol Chem 285 2010 33520–33528 http://dx.doi.org/10.1074/jbc.M110.158378.

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Cyclodextrin-complexed curcumin exhibits anti-inflammatory and antiproliferative activities superior to those of curcumin through higher cellular uptake

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