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Autoimmunity as the Consequence of a Spontaneous Mutation in Rasgrp1  

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Resource details

Resource ID

67

Default
Publication
Retraction
Retraction Case 1

Date

09 May 2019

Authors

Katrin Layer, Guosheng Lin, Alessio Nencioni, Wei Hu , Adam Schmucker, Andrey N. Antov, Xiaoyu Li, Satoshi Takamatsu, Timothy Chevassut, Nancy A. Dower, Stacey L. Stang, David Beier, Janet Buhlmann, Roderick T. Bronson, Keith B. Elkon, James C. Stone, Luk Van Parijs, Bing Lim

Publisher

Elsevier

Journal

Immunity

Subjects

BLS - Basic Life Sciences/Biology - Cellular,HSC - Human Science/Medicine/Medicine - Immunology,PUB - Publishing/Society/Association Journals

Publication Date

01 August 2003

DOI

10.1016/S1074-7613(03)00209-7

Retraction DOI

10.1016/j.immuni.2012.05.007

Related links

https://pubpeer.com/publications/837D86DED7B9054AEFBA020649C50A

http://retractionwatch.com/2012/05/30/an-immunity-retration-for-luk-van-parijs-three-years-after-the-ori-found-evidence-of-fabrication-in-the-paper/

Image Type

Western Blot

Manipulated Image

6A

Manipiulation category 1

not specified

Comment 1

"The authors have agreed to retract the paper because of the falsification of the Western blot in Figure 6A. The figure shows a defect in Ras activation, labeled as RasGTP, following TCR engagement, in thymocytes isolated from a RasGRP1 lag mutant mouse strain." (See Retraction Notice)

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